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Estimating genetic correlations based on phenotypic data: a simulation-based method

机译:基于表型数据估计遗传相关性:一种基于模拟的方法

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摘要

Knowledge of genetic correlations is essential to understand the joint evolution of traits through correlated responses to selection, a difficult and seldom, very precise task even with easy-to-breed species. Here, a simulation-based method to estimate genetic correlations and genetic covariances that relies only on phenotypic measurements is proposed. The method does not require any degree of relatedness in the sampled individuals. Extensive numerical results suggest that the propose method may provide relatively efficient estimates regardless of sample sizes and contributions from common environmental effects.
机译:遗传相关知识对于通过对选择的相关反应了解性状的共同进化是必不可少的,即使对于容易繁殖的物种,这也是一项困难而很少且非常精确的任务。在这里,提出了一种基于模拟的估计遗传相关性和遗传协方差的方法,该方法仅依赖于表型测量。该方法在被采样的个体中不需要任何程度的相关性。大量的数值结果表明,所提出的方法可以提供相对有效的估计,而与样本大小和常见环境影响的贡献无关。

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