The volume of vaccine analytical literature is notable (the journal Vaccine along having pub- lished 231 trials on different vaccines between 1983 and 1994). However, to date little atten- tion has been paid to summarising and evaluating its significance in the assessment of vaccine quality (defined as efficacy, effective- ness, efficiency, safety, and acceptability). Quality assessment is important as vaccines are A widely used preventive technology, vaccina- Tion programmes are mostly publicly funded, And decisions to immunise whole populations Must be made on the best available evidence, Especially if such practice is regulated by law.
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