Comparison of calculated and measured Ⅰ-Ⅴ curves for DNA

摘要

Cohen et al. have reported experimental observations of current passing through the dsDNA molecules using a metal-covered atomic force microscope (AFM) tip; the molecules are chemically connected to a metal substrate at one end and to a gold nanoparticle (GNP) at the opposite end. They have presented evidence for charge transport through dsDNA molecules of a complex sequence, 26 bp long, characterized by S-shaped current-voltage (Ⅰ-Ⅴ) curves. In this paper, theoretical calculations giving excellent agreement with the results of Cohen et al. are obtained using the formalism of Datta et al.