Utilizing switching technique to develop the sequential injection of discrete sample plugs in a microfluidic device

摘要

This study proposes a technique for the discrete injection of electro-osmotically-driven sample flows in a microfluidic device. The numerical results confirm that the sample plug flow can be produced by electrokinetically pre-focusing and switching, and then guided to the desired outlet port by means of a simple control voltage model. The results show that a microfluidic chip is capable not only of generating a single length plug sample flow to a specified output port, but is also able to generate a series of different length plug samples. Utilizing electrokinetically pre-focused micro flow switching, two grounding times (1.4 and 1.8 s) are assigned to cycle in reservoir 1, two different sample lengths are generated in channel-a. The results of this study provide a useful methodology for the analysis of flow control in microfluidic devices.View full textDownload full textKeywordsmicrofluidics, electrokinetic injection, sequential injectionRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/02533839.2011.565608