TCR Vβ17 gene polymorphism in wild populations of Indian Mus musculus

摘要

The Indian house mouse populations, in addition to extreme polymorphism for nuclear genes encoding for various isozymes and mitochondrial DNA also show a high level of variation for the TCR Vβ17 gene. RFLP analysis has revealed six variant forms of the gene which are classified on the basis of size of the restriction fragment. These forms are not present in the laboratory inbred strains. The new alleles are present at different frequencies in nine Indian localities.