Low-Power Picosecond Resonance Raman Evidence for Histidine Ligation to Heme a_3 after Photodissociation of CO from Cytochrome c Oxidase

摘要

Several models have been proposed for the ligand dynamics in the heme a_3~2+/Cu_B~1+ binuclear pocket in cytochrome oxidase following CO photodissociation. These range from straightforward heme pocket relaxation to a variety of ligand exchange processes hat have been proposed to be of relevance to the proton pumping function of the enzyme.