Three-Dimensional Molding Based on Microstereolithography Using Beta-Tricalcium Phosphate Slurry for the Production of Bioceramic Scaffolds

摘要

We report on a three-dimensional (3D) molding technique of fabricating bioceramic scaffolds. In this method, ceramic slurry is cast into a 3D polymer master mold, which is fabricated via microstereolithography, by a centrifugal casting method. The polymer master mold is thermally decomposed, so that a complex 3D bioceramic scaffold can be produced. In experiments, the decomposition process of the polymer model was optimized by the master decomposition curve theory to reduce harmful cracks in a green body. As a result, we could produce not only precise lattice models but also a sophisticated porous scaffold using beta-tricalcium phosphate (/3-TCP) slurry. This bioceramic 3D molding technique based on microstereolithography will be useful for tailor-made tissue engineering and regeneration medicine.