A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma

Karl Bélanger; David MacDonald; Gregory Cairncross; Stan Gertler; Peter Forsyth; Susan Burdette-Radoux; Julie Bergeron; Denis Soulières; Samuel Ludwin; Nancy Wainman; Elizabeth Eisenhauer

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A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma

机译：拓扑替康在间变性少突胶质细胞瘤或间变性混合少突星形胶质细胞瘤患者中的II期研究

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摘要

To determine the efficacy and toxicity of a novel chemotherapeutic approach with topotecan, a camptothecin analog, for progressive or recurring anaplastic oligodendroglioma or mixed oligoastrocytoma.

机译：为了确定新型化学疗法与拓扑替康（喜树碱类似物）对进行性或复发性间变性少突胶质细胞瘤或混合性少星形胶质细胞瘤的疗效和毒性。

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来源
《Investigational New Drugs》 |2003年第4期|473-480|共8页
作者
Karl Bélanger; David MacDonald; Gregory Cairncross; Stan Gertler; Peter Forsyth; Susan Burdette-Radoux; Julie Bergeron; Denis Soulières; Samuel Ludwin; Nancy Wainman; Elizabeth Eisenhauer;
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作者单位

CHUM-Hôpital Notre-Dame Department of Hematology;

London Regional Cancer Centre;

London Regional Cancer Centre;

Ottawa Regional Cancer Centre;

Tom Baker Cancer Centre;

Department of Oncology McGill University;

CHUM-Hôpital Notre-Dame Department of Hematology;

CHUM-Hôpital Notre-Dame Department of Hematology;

Department of Pathology Queen's University;

NCIC Clinical Trials Group Queen's University;

NCIC Clinical Trials Group Queen's University;

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原文格式 PDF
正文语种 eng
中图分类
关键词
topotecan; oligodendroglioma; phase II;

机译：拓扑替康;少突胶质瘤;II期;

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专利

1. A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma. [J] . Belanger K, MacDonald D, Cairncross G, Investigational new drugs. . 2003,第4期

机译：拓扑替康在间变性少突胶质细胞瘤或间变性混合少突星形胶质细胞瘤患者中的II期研究。
2. Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131 [J] . Vogelbaum Michael A., Hu Chen, Peereboom David M., Journal of neuro-oncology. . 2015,第3期

机译：新诊断的间变性少突胶质细胞瘤和间变性少突星形胶质细胞瘤患者的放疗前和同时替莫唑胺II期试验：RTOG BR0131的长期结果
3. Phase Ii Trial Of Preirradiation And Concurrent Temozolomide In Patients With Newly Diagnosed Anaplastic Oligodendrogliomas And Mixed Anaplastic Oligoastrocytomas: Rtog Br0131 [J] . Michael A. Vogelbaum, Brian Berkey, David Peereboom, Neuro-Oncology . 2009,第2期

机译：新诊断为间变性少突胶质细胞瘤和间变性少突星形胶质细胞瘤的患者的放射线照射和同期替莫唑胺II期试验：Rtog Br0131
4. Efficacy Analysis of Preservative-Free Tafluprost and Timolol in Open-Angle Glaucoma and OHT Patients in a Phase-III Study [C] . GrundenJ., Lupinacci R. International Symposium on Ocular Pharmacology and Therapeutics . 2013

机译：在第三阶段研究中，在开放角度荧光眼和OHT患者中无防腐型TaFluprost和蒂莫尔的疗效分析
5. The Role of Online Support for Anaplastic Thyroid Cancer Patients and Survivors [D] . Nixon, Bevin J. 2019

机译：在线支持对共产性甲状腺癌患者和幸存者的作用
6. Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131 [O] . Michael A. Vogelbaum, Brian Berkey, David Peereboom, 2009

机译：RTOG BR0131在新诊断的间变性少突神经胶质瘤和混合间变性少突星形胶质细胞瘤患者中进行放疗前和同时进行的替莫唑胺II期试验：RTOG BR0131
7. Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131 [O] . Michael A. Vogelbaum, Chen Hu, David M. Peereboom, 2015

机译：新诊断的内塑性少突术患者预防和同时替代毒物蛋白酶II试验和混合促进橄榄球子沟槽瘤：RTOG的长期结果BR0131

A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma

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