Tumor necrosis factor-α promoter polymorphism TNF2 is associated with a stronger delayed-type hypersensivity reaction in the skin of borderline tuberculoid leprosy patients

Milton O. Moraes; Nádia C. Duppre; Philip N. Suffys; Adalberto R. Santos; Alexandre S. Almeida; José A. C. Nery; Elizabeth P. Sampaio; Euzenir N. Sarno

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Tumor necrosis factor-α promoter polymorphism TNF2 is associated with a stronger delayed-type hypersensivity reaction in the skin of borderline tuberculoid leprosy patients

机译：肿瘤坏死因子-α启动子多态性TNF2与交界性结核性麻风患者皮肤中较强的迟发型超敏反应有关

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来源
《Immunogenetics》 |2001年第1期|45-47|共3页
作者
Milton O. Moraes; Nádia C. Duppre; Philip N. Suffys; Adalberto R. Santos; Alexandre S. Almeida; José A. C. Nery; Elizabeth P. Sampaio; Euzenir N. Sarno;
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作者单位

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Laboratory of Molecular Biology and Diagnosis of Infectious Diseases Department of Biochemistry and Molecular Biology Oswaldo Cruz Institute FIOCRUZ Rio de Janeiro RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

Leprosy Laboratory Tropical Medicine Department Oswaldo Cruz Institute FIOCRUZ. Av.Brasil 4365. Manguinhos Rio de Janeiro 21045-900 RJ Brazil;

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原文格式 PDF
正文语种 eng
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关键词
TNFα Leprosy Polymorphism Mycobacteria Promoter;

机译：TNFα麻风病多态性分枝杆菌启动子;

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专利

1. Tumor necrosis factor promoter polymorphism (TNF2) seems to protect against development of severe forms of leprosy in a pilot study in Brazilian patients. [J] . Santos AR, Almeida AS, Suffys PN, International Journal of Leprosy and Other Mycobacterial Diseases . 2000,第3期

机译：在一项针对巴西患者的初步研究中，肿瘤坏死因子启动子多态性（TNF2）似乎可以预防严重麻风病的发展。
2. Immune reconstitution inflammatory syndrome or upgrading type 1 reaction? Report of two AIDS patients presenting a shifting from borderline lepromatous leprosy to borderline tuberculoid leprosy. [J] . Talhari C, Ferreira LC, Araujo JR, Leprosy review . 2008,第4期

机译：免疫重建炎症综合症或1型反应升级？两名艾滋病患者从边缘性麻风麻风病转变为边缘性结核麻风病的报告。
3. A rare case of type 1 leprosy reactions following tetanus infection in a borderline tuberculoid leprosy patient and a literature review [J] . Chao Shi, Zhi-Chun Jing, De-Gang Yang, 贫困所致传染病（英文） . 2018,第001期

机译：Tetanus感染后破伤风结核麻风病变患者稀有1型麻风病反应的病例和文献综述
4. A rare case of type 1 leprosy reactions following tetanus infection in a borderline tuberculoid leprosy patient and a literature review [O] . Chao Shi, Zhi-Chun Jing, De-Gang Yang, 2018

机译：交界性结核性麻风患者破伤风感染后罕见的1型麻风反应病例及文献复习
5. Association of a Promoter Polymorphism of Tumor Necrosis Factor-α with Subacute Cutaneous Lupus Erythematosus and Distinct Photoregulation of Transcription1,21Werth VP, Sullivan K: Strong association of a promoter polymorphism of tumor necrosis factors α with a photosensitive form of cutaneous lupus erythematosus. Arthr Rheum 42:S105 1999 (abstr.)2Werth VP, Zhang W, Sullivan K: Role of a promoter polymorphism of tumor necrosis factor-α (TNF-α) in a photosensitive form of lupus erythematosus (LE): clinical association and distinct photoregulation of transcription. J Invest Dermatol 114:770 2000 (abstr.) [O] . Werth Victoria P., Zhang Wei, Dortzbach Kathy, 2000

机译：肿瘤坏死因子-α启动子多态性与亚急性皮肤性红斑狼疮和转录的明显光调节相关1,21Werth VP，Sullivan K：肿瘤坏死因子α的启动子多态性与光敏性皮肤性红斑狼疮有很强的联系。 Arthr Rheum 42：S105 1999（摘要）2沃特VP，张W，沙利文K：肿瘤坏死因子-α（TNF-α）启动子多态性在红斑狼疮（LE）的光敏形式中的作用：临床关联和独特之处转录的光调节。 J投资皮肤病杂志114：770 2000（摘要）

Tumor necrosis factor-α promoter polymorphism TNF2 is associated with a stronger delayed-type hypersensivity reaction in the skin of borderline tuberculoid leprosy patients

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