Effects of atrioventricular asynchrony on platelet activation: implication of thromboembolism in paced patients

摘要

Conclusions-Single chamber ventricular pacing was associated with enhanced spontaneous systemic platelet activation compared with physiological dual cham- ber pacing. This was related to the loss of atrioventricular synchrony rather than to the underlying cause of bradycardia, lack of rate response, or coexisting arrhyth- mia. This abnormality may be associated with increased thromboembolism and was correctible by an appropriate pacing mode prescription and possibly antiplate- let treatment.