The time dependence for successful reperfusion after thrombolytic treatment has motivated many strategies for reducing the delay between onset of symptoms and drug administration. Most of the delay is inevitably in the pre- hospital phase and thus difficult to influence. Even after hospital admission an hour or so may elapse before definitive treatments is started but this can more readily be addressed. Jargon phases such as "door to needle time" and "time is muscle" were introduced to emphasise the need for rapid assessment and initiation of therapy.
展开▼
