Non-invasive measurement of endothelial function: effect on brachial artery dilatation of graded endothelial dependent and independent stimuli

摘要

Conclusions-Measures of arterial func- tion vary with duration of blood flow occlusion and ISDN dose. Maximum arterial response was reached in all sub- jects after 4·5 minutes of blood flow occlu- sion or 200 μg of ISDN. Therefore, these variables produce consistent reproducible measures of endothelial function. Objective-To examine the relation Between endothelial dependent and Endothelial independent stimuli of vary- Ing intensity and measures of vascular Function in the brachial artery of young Healthy adults, to determine whether These responses are consistent and can be Used to assess endothelial function.