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Missing data resilient decision-making for healthcare IoT through personalization: A case study on maternal health

机译:通过个性化缺少医疗物联网的数据弹性决策:孕产妇保健案例研究

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Remote health monitoring is an effective method to enable tracking of at-risk patients outside of conventional clinical settings, providing early-detection of diseases and preventive care as well as diminishing healthcare costs. Internet-of-Things (IoT) technology facilitates developments of such monitoring systems although significant challenges need to be addressed in the real-world trials. Missing data is a prevalent issue in these systems, as data acquisition may be interrupted from time to time in long-term monitoring scenarios. This issue causes inconsistent and incomplete data and subsequently could lead to failure in decision making. Analysis of missing data has been tackled in several studies. However, these techniques are inadequate for real-time health monitoring as they neglect the variability of the missing data, This issue is significant when the vital signs are being missed since they depend on different factors such as physical activities and surrounding environment. Therefore, a holistic approach to customize missing data in real-time health monitoring systems is required, considering a wide range of parameters while minimizing the bias of estimates. In this paper, we propose a personalized missing data resilient decision-making approach to deliver health decisions 24/7 despite missing values. The approach leverages various data resources in IoT-based systems to impute missing values and provide an acceptable result. We validate our approach via a real human subject trial on maternity health, in which 20 pregnant women were remotely monitored for 7 months. In this setup, a real-time health application is considered, where maternal health status is estimated utilizing maternal heart rate. The accuracy of the proposed approach is evaluated, in comparison to existing methods. The proposed approach results in more accurate estimates especially when the missing window is large. (C) 2019 The Authors. Published by Elsevier B.V.
机译:远程健康监测是一种有效的方法,可以跟踪常规临床环境之外的高危患者,提供疾病的早期发现和预防性护理,并降低医疗成本。物联网(IoT)技术促进了此类监控系统的开发,尽管在实际试验中需要解决重大挑战。在这些系统中,数据丢失是一个普遍存在的问题,因为在长期监视情况下,数据采集可能会不时中断。此问题导致数据不一致和不完整,并随后可能导致决策失败。几项研究已经解决了缺失数据的分析问题。但是,由于这些技术忽略了丢失数据的可变性,因此不足以进行实时健康监测。当生命体征丢失时,此问题就很重要,因为它们取决于身体活动和周围环境等不同因素。因此,需要一种整体方法来在实时健康监视系统中自定义丢失的数据,同时考虑各种参数,同时将估计偏差最小化。在本文中,我们提出了一种个性化的缺失数据弹性决策方法,尽管存在缺失值,但仍可以24/7提供健康决策。该方法利用基于物联网的系统中的各种数据资源来估算缺失值并提供可接受的结果。我们通过一项关于孕产妇健康的真实人类试验来验证我们的方法,该试验对20名孕妇进行了7个月的远程监测。在此设置中,考虑了实时健康应用程序,其中利用产妇的心率估计了产妇的健康状况。与现有方法相比,评估了所提出方法的准确性。所提出的方法导致更准确的估计,尤其是当丢失的窗口很大时。 (C)2019作者。由Elsevier B.V.发布

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