the prevalence and possible causes of bound and extractable residues of the furazolideone metabolite 3-amino-2-oxazolidinone in porcine tissues

摘要

Furazolidone is readily metabolized and rarely detect- able in animal tissues. An alternative is to measure bound and extractable residues containing the 3-amino- 2-oxazolidinone (AOZ) moiety. This compound was used to examine the incidence of furazolidone residues in Northern Ireland pigs. AOZ was found in 32/200 kidney samples. A depletion study showed that none of the samples contained AOZ residues at concentrations greater than that found in pigs fed medicated feed, and subjected to an obligatory 7-day withdrawal period.