Gastrointestinal tolerance of γ-cyclodextrin in humans

摘要

The gastrointenstinal tolerance of γ-cyclodextrin (γ- CD) was examined in 24 healthy human volunteers. In A double-blind, placebo-controlled, randomized cros- Over study, single acute doses of 8 g maltodextrin (placebo) or 8 g γ-CD (test) were consumed as a mid-morning snack after addition to 100 g yogurt. Gastrointenstinal symptoms as well as frequency and Consistency of stools were recorded before and after Lunch at between 3-4 and 7-8 h after intake respect- Ively.