Development of a Diet for Long-Term Raising of F344 Rats -Relationship between Dietary digestible Crude Protein Content and Digestible Energy Content-

摘要

Mice and rats are frequently subjected to long-term raising in studies of aging. These animals are usually given growing or breeding diets from a young age. This raising Method causes diseases such as chronic nephropathy with proteinuria due to nutritional Excess. Consequently, a long-term raising study on male F344/DuCrj rats using nine sorts Of diets differing in crude protein (CP; 12, 28, 44/100) sand digestible energy (DE; 2.8, 3.7, 4.5 Kcal/g) contents was carried out. It was found that feed consumption was regulated by DE, Not digestible crude protein (DCP) intake.