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Different Pattern of Pinopodes Expression in Stimulated Mouse Endometrium

机译:在受刺激的小鼠子宫内膜中不同的Pinopodes表达模式

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Adult NMRI mice were superovulated using human menopausual chorionic gonadotropic hormones (hMG and hCG), and then some of them were daily injected with progesterone (1 mg/mouse). At 3.5 and 4.5 days after hCG injection scanning electron micrographs revealed that the hyperstimulated and progesterone-injected group had well-developed pinopodes while most of the hyperstimulated group without progesterone injection had no pinopodes 3.5 days after stimulation. The results suggest that the lifespan of pinopodes is short and changeable during hyperstimulation and that progesterone causes premature formation of the pinopodes and that implantation after ovarian stimulation might depend upon the timing of the pinopode expression.
机译:使用人类更年期绒毛膜促性腺激素(hMG和hCG)对成年NMRI小鼠进行超排卵,然后每天对其中的一些小鼠进行孕激素注射(1毫克/小鼠)。 hCG注射后3.5天和4.5天,扫描电子显微镜照片显示,过度刺激和孕酮注射组具有成熟的pinopodes,而大多数未注射孕激素的过度刺激组在刺激后3.5天没有pinopodes。结果表明,在过度刺激过程中,pinodes的寿命很短且可改变,孕激素会导致pinodes的过早形成,卵巢刺激后的植入可能取决于pinode的表达时间。

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