Age-Related Changes in Antioxidant Enzyme Activities in the Small Intestine and Liver from Wistar Rats

摘要

The present study was designed to determine age-related changes in intestinal and hepatic antioxidant enzymes including superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), and glutathione-S- transferase (GST), and lipid peroxidation in male Wistar rats (n=8) aged 2 wk, 2.5 mon, 5 mon, 10 mon, and 23 mon. In the small intestine, Cytosolic SOD, GSH-PX activities and lipid peroxidation were not affected by age, but Intestinal GST activity was noticeably enhanced as age increased.