Macroscopic Distribution of Coronary Atherosclerotic lesions in Cholesterol-fed Rabbits

摘要

In the present study we macroscopically examined a change in the distribution of coronary atherosclerosis in cholesterol-red rabbits. Rabbits were fed a cholesterol-enriched diet for 15 weeks, then replaced by a normal diet, and were sacrificed at 15, 24, 32 and 42 weeks after the start of the experiment. The coronary atheroscelrosis in the cholesterol-fed rabbits was distributed more densely in the proximal portion than in the middle and distal portions, and the lesions were severe at 24 and 32 weeks after the start of the experiment.