Extension of Conserved Regions in the Rat and Mouse Genomes by Chromosomal Assignments of 29 Rat Genes

摘要

We recently constructed a comparative genetic map of the rat, mouse and human genomes based on information obtained from several databases. In this study, we performed chromosomal assignments of 299 rat genes with somatic cell hybrid clones, in order to clarify and extent the conserved regions in the rat and mouse genomes. As a result, the conserved regions were extended by 89 cM. Together with our previous report, the length of the conserved regions in the rat and mouse spans 847 cM on the mouse linkage map, indicating that 53 /100 of the mouse genome is covered by homologous regions in the rat.