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Renal Carbonic Anhydrase Activity in DBA/2FG-pcy/pcy Mice with Inherited Polycystic Kidney Disease

机译:DBA / 2FG-pcy / pcy遗传性多囊肾病小鼠的肾脏碳酸酐酶活性

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摘要

DBA/2FG-pcy/pcy (D2-pcy) mice are a hereditary murine model of slowly progressive polycystic kidney disease (PKD) and characterized by the persistent excretion of acidic urine, in association with polyuria, after weaning. In this study, the activity of carbonic anhydrase (CA) and it histological distribution in the kidney of D2-pcy mice were investigated by immunohistochemistry.
机译:DBA / 2FG-pcy / pcy(D2-pcy)小鼠是一种缓慢进展的多囊肾病(PKD)的遗传性小鼠模型,其特征是断奶后与多尿症有关的酸性尿液持续排泄。在这项研究中,通过免疫组织化学研究了碳酸酐酶(CA)的活性及其在D2-pcy小鼠肾脏中的组织学分布。

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