aPeripheral Mononeuropathy Induced by Loose Ligation of the Sciatic Nerve in the Rat: Behavioral,

摘要

The relationship between clinical parameters and pathological changes was investigated in an animal model of mononeuropathy, by behavioral, electrophysiological and histopathological methods. Monoeuropathy was induced in rats by loosely typing ligatures around the sciatic nerve. Eighty-four rats were used, and these were divided into fourteen groups to determine chronological changes in the withdrawal reflex latency, nerve conduction velocity and ultrastructure of the nerve from 1 to 84 days after nerve ligation surgery.