Relationships between thiopurine S-methyltransferase polymorphism and azathioprine-related adverse drug reactions in Chinese renal transplant recipients

Hua-Wen Xin; Hui Xiong; Xiao-Chun Wu; Qing Li; Lei Xiong; Ai-Rong Yu

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Relationships between thiopurine S-methyltransferase polymorphism and azathioprine-related adverse drug reactions in Chinese renal transplant recipients

机译：中国肾移植受者硫嘌呤S-甲基转移酶基因多态性与硫唑嘌呤相关药物不良反应的关系

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Objective To systematically investigate the relationships between thiopurine S-methyltransferase (TPMT) polymorphisms and azathioprine-related adverse drug reactions in patients with kidney transplantation.

机译：目的系统研究硫嘌呤S-甲基转移酶（TPMT）基因多态性与肾移植患者硫唑嘌呤相关药物不良反应的关系。

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《European Journal of Clinical Pharmacology》 |2009年第3期|p.249-255|共7页
作者
Hua-Wen Xin; Hui Xiong; Xiao-Chun Wu; Qing Li; Lei Xiong; Ai-Rong Yu;
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正文语种 eng
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关键词
Adverse drug reactions; Azathioprine; Genetic polymorphisms; Renal transplantation; TPMT activity;

机译：药物不良反应;硫唑嘌呤;遗传多态性;肾移植;TPMT活动;

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专利

1. Relationships between thiopurine S-methyltransferase polymorphism and azathioprine-related adverse drug reactions in Chinese renal transplant recipients. [J] . Xin HW, Xiong H, Wu XC, European journal of clinical pharmacology . 2009,第3期

机译：中国肾移植受者中硫嘌呤S-甲基转移酶多态性与硫唑嘌呤相关的不良药物反应之间的关系。
2. Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients [J] . Hui Xiong, Hua Wen Xin, Xiao Chun Wu, Fundamental & clinical pharmacology. . 2010,第3期

机译：肌苷三磷酸焦磷酸水解酶缺乏与中国肾脏移植受者硫唑嘌呤相关的不良药物反应之间的关系
3. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism. [J] . Schwab M, Schaffeler E, Marx C, Pharmacogenetics . 2002,第6期

机译：硫唑嘌呤治疗和炎性肠病患者的药物不良反应：硫嘌呤S-甲基转移酶多态性的影响。
4. ASSOCIATION OF CYP3A4 * 18B POLYMORPHISMS WITH THE PHARMACOKINETICS OF TACROLIMUS IN CHINESE RENAL TRANSPLANT RECIPIENTS [C] . Li Danying, Fang Yun, Teng Ruichen Progress on post-genome technologies and modern natural products . 2011

机译：CYP3A4 * 18B多态性与中国肾移植患者滑石M药代动力学的关系
5. Characterization of renal anionic drug transport capacity in kidney transplant recipients with persistent BK viremia: Pharmacokinetic and pharmacodynamic studies of cidofovir. [D] . Momper, Jeremiah D. 2011

机译：持续性BK病毒血症的肾脏移植受者中肾脏阴离子药物转运能力的表征：西多福韦的药代动力学和药效学研究。
6. Association between Thiopurine S-methyltransferase Polymorphisms and Thiopurine-Induced Adverse Drug Reactions in Patients with Inflammatory Bowel Disease: A Meta-Analysis [O] . Yue-Ping Liu, Hai-Yan Wu, Xiang Yang, -1

机译：炎症性肠病患者硫嘌呤S-甲基转移酶多态性与硫嘌呤诱导的不良药物反应之间的关联：荟萃分析
7. Association between thiopurine S-methyltransferase polymorphisms and thiopurine-induced adverse drug reactions in patients with inflammatory bowel disease: a meta-analysis. [O] . Yue-Ping Liu, Hai-Yan Wu, Xiang Yang, 2015

机译：炎症性肠病患者中硫嘌呤s-甲基转移酶基因多态性与硫嘌呤诱导的药物不良反应的关联：荟萃分析。

Relationships between thiopurine S-methyltransferase polymorphism and azathioprine-related adverse drug reactions in Chinese renal transplant recipients

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