Elucidating the Stimulatory and Inhibitory Effects of Dissolved Organic Matter from Poultry Litter on Photodegradation of Antibiotics

摘要

This study examined the photolytic fate of the chlortetracycline (CTC), ciprofloxacin (CIP), roxarsone (ROX), and sulfamethoxazole (SMX) antibiotics in agriculturally relevant matrices. The observed photodegradation kinetics for antibiotics in solutions containing dissolved organic matter (DOM) from three poultry Utter extracts was modeled to identify contributions from direct and indirect photolysis. Suwannee River natural organic matter (SRN) was used as a surrogate DOM standard. Poultry litter-derived DOM generated lower concentrations of reactive spedes compared to SRN. Direct photolysis was the dominant transformation mechanism for CIP, whereas CTC, ROX, and SMX were sensitized by ~3DOM* and 1O_2. The impacts of agricultural DOM on photodegradation of antibiotics were identified in terms of pseudo-first-order rate constants for formation of reactive species and second-order rate constants for reaction of reactive species with DOM. Solutions containing poultry litter-derived DOM generated similar levels of ~3DOM* and ~1O_2 enhancing degradation of CTC, ROX, and SMX. The reactivity of SMX was markedly different in solutions containing poultry litter DOM compared to solutions with SRN, indicating that the photolytic fate of select antibiotics varies for agricultural and surface water matrices. As the majority of antibiotics are consumed by animals, these findings provide new insight into agriculturally relevant transformation mechanisms and kinetics.