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Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities

机译:估算细颗粒和粗颗粒污染对中国六个亚热带城市中风死亡率的急性影响

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摘要

While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 mu g/m(3) increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88% (95% CI: 137%, 2.39%), 3.07% (95% Cl: 2.35%, 3.79%), and 5.72% (95% CI: 3.82%, 7.65%) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21% (95% CI: 1.65%, 3.01%) of stroke mortality (corresponding to 1743 stroke mortalities, 95% CI: 896, 1633) were attributed to PM10, 5.57% (95% CI: 0.50%, 1.23%) stroke mortality (3019, 95% CI: 2286, 3777) were attributed to PM2.5, and 2.02% (95% CI: 1.85%, 3.08%) of stroke mortality (1097, 95% CI: 1005, 1673) could be attributed to PM10-2.5. Our analysis indicates that both PM2.5 and PM10-2.5 are important risk factors of stroke mortality and should be considered in the prevention and control of stroke in the study area. (C) 2018 Elsevier Ltd. All rights reserved.
机译:虽然越来越多的证据表明PM2.5是颗粒污染物中最有害的部分,但粗颗粒(PM10-2.5)的健康影响尚无定论,尤其是对脑血管疾病,因此我们评估了PM10,PM2.5,使用广义加性模型对中国六个亚热带城市的卒中死亡率进行PM10-2.5评估。我们还进行了随机效应荟萃分析,以评估六个城市的总体效应。我们发现PM10,PM2.5和PM10-2.5与中风死亡率显着相关。 PM10,PM2.5和PM10-2.5(lag03)每增加10μg/ m(3),则分别增加1.88%(95%CI:137%,2.39%),3.07%(95%Cl:总卒中死亡率分别为2.35%,3.79%和5.72%(95%CI:3.82%,7.65%)。使用世界卫生组织的指南作为参考浓度,我们估计卒中死亡率(对应于1743例卒中死亡率,95%可信区间:896、1633)的卒中死亡率的3.21%(95%CI:1.65%,3.01%)归因于PM10、5.57 %(9519 CI:0.50%,1.23%)中风死亡率(3019,95%CI:2286,3777)归因于PM2.5,而2.02%(95%CI:1.85%,3.08%)归因于PM2.5( 1097、95%CI:1005、1673)可归因于PM10-2.5。我们的分析表明,PM2.5和PM10-2.5都是中风死亡率的重要危险因素,在研究区域的中风预防和控制中应予以考虑。 (C)2018 Elsevier Ltd.保留所有权利。

著录项

  • 来源
    《Environmental Pollution》 |2018年第8期|812-817|共6页
  • 作者单位

    Sun Yat Sen Univ, Sch Publ Hlth, Dept Med Stat & Epidemiol, Guangzhou 510080, Guangdong, Peoples R China;

    St Louis Univ, Coll Publ Hlth & Social Justice, St Louis, MO 63104 USA;

    Guangzhou Ctr Dis Control & Prevent, Guangzhou 511430, Guangdong, Peoples R China;

    Sun Yat Sen Univ, Dept Neurol, Affiliated Hosp 1, 58 Zhongshan Rd 2, Guangzhou 510080, Guangdong, Peoples R China;

    Sun Yat Sen Univ, Sch Publ Hlth, Dept Med Stat & Epidemiol, Guangzhou 510080, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Inst Chron Noncommunicable Dis Control & Prevent, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Inst Chron Noncommunicable Dis Control & Prevent, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Pharmaceut Univ, Sch Publ Hlth, Guangzhou 510220, Guangdong, Peoples R China;

    Sun Yat Sen Univ, Sch Publ Hlth, Dept Med Stat & Epidemiol, Guangzhou 510080, Guangdong, Peoples R China;

    St Louis Univ, Coll Publ Hlth & Social Justice, St Louis, MO 63104 USA;

    St Louis Univ, Coll Publ Hlth & Social Justice, St Louis, MO 63104 USA;

    Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Guangdong, Peoples R China;

    Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Guangdong, Peoples R China;

    Sun Yat Sen Univ, Sch Publ Hlth, Dept Med Stat & Epidemiol, Guangzhou 510080, Guangdong, Peoples R China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Air pollution; Particulate matter; Stroke; China;

    机译:空气污染;颗粒物;中风;中国;
  • 入库时间 2022-08-17 13:25:54

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