Exposure Assessment Of French Women And Their Newborn To Brominated Flame Retardants: Determination Of Tri- To Deca- Polybromodiphenylethers (pbde) In Maternal Adipose Tissue, Serum, Breast Milk And Cord Serum

摘要

In the frame of a French monitoring program, tri- to deca- polybromodiphenylethers (PBDE) have been measured in maternal and cord serum, adipose tissue, and breast milk samples, collected from 93 volunteer women during caesarean deliveries. The seven major tri- to heptaBDE (BDE-28,47,99,100,153, 154, and 183) were detected in adipose tissue and breast milk with cumulated median values of 2.59 and 2.51 ng g~(-1) lw. Nine highly brominated octa- to decaBDE (BDE-196,197,201, 202,203,206, 207, 208 and 209) was performed in the same samples, with cumulated median values of 2.73 and 3.39 ng g~(-1) lw in adipose tissue and breast milk, respectively. At this opposite, median levels of octa- to decaBDE in maternal and cord serum appeared significantly higher than the levels of tri- to heptaBDE in the same matrices, i.e. 8.85 and 12.34 versus 0.98 and 0.69 ng g~(-1) lw, respectively.