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首页> 外文期刊>Digestive Diseases and Sciences >Inhibition of Pim-1 Kinase Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mice
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Inhibition of Pim-1 Kinase Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mice

机译：Pim-1激酶的抑制作用改善了葡聚糖硫酸钠诱导的小鼠结肠炎

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摘要

Pim-1 kinase is involved in the control of cell growth, differentiation and apoptosis. Recent evidence suggests that Pim kinases play a role in immune regulation and inflammation. However, the role of Pim-1 kinase in inflammatory bowel diseases (IBD) remains unclear.
机译：Pim-1激酶参与细胞生长，分化和凋亡的控制。最近的证据表明，Pim激酶在免疫调节和炎症中起作用。但是，尚不清楚Pim-1激酶在炎症性肠病（IBD）中的作用。

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  • 来源
    《Digestive Diseases and Sciences 》 |2012年第7期| p.1822-1831| 共10页
  • 作者

    Yue-Ming Shen; Yan Zhao; Ya Zeng; Lu Yan; Bo-Lin Chen; Ai-Min Leng; Yi-Bin Mu; Gui-Ying Zhang;

  • 作者单位

    Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, People’s Republic of China;

    Department of Pathology, The Fourth Hospital of Changsha, Changsha, People’s Republic of China;

    Department of Digestive Diseases, Changsha Central Hospital, Changsha, People’s Republic of China;

    Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, People’s Republic of China;

    Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, People’s Republic of China;

    Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, People’s Republic of China;

    Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, People’s Republic of China;

    Department of;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Pim-1 kinase; Inflammatory bowel diseases; Pim-1 kinase inhibitor; Macrophage; T-Lymphocyte subsets; NF-kappa B;

    机译：Pim-1激酶;炎性肠病;Pim-1激酶抑制剂;巨噬细胞;T淋巴细胞亚群;NF-κB;

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