Effect of Intensive Diabetes Treatment on Carotid Artery Wall Thickness in the Epidemiology of Diabetes Interventions and Complications

摘要

The Epidemiology of Diabetes Interventions and Com- plications (EDIC) is a multicenter longitudinal obser- vational study of the Diabetes Control and Complica- tions Trial (DCCT) cohort. One of the major objectives of EDIC is to study the development and progression of atherosclerotic cardiovascular disease in type 1 dia- betes. In this study, we evaluated the role of cardio- vascular risk factors and antecedent therapy in the DCCT on carotid intima-media wall thickness (IMT) in Type 1 diabetes, 19-51 years of age, with duration Of diabetes ranging from 6.3 to 26.1 years. An age- and Sex-matched nondiabetic population (n=153) was Studied with the same protocol.