Plasma Leptin and Insulin Levels in Weight-Reduced Obese Women With Normal Body Mass Index: Relationships With Body Composition and Insulin

摘要

Obesity is a complex disease with multiple features that has confounded efforts to unravel its pathophysiology As a means of distinguishing primary from secondary Characteristics, we compared levels of fasting plasma Leptin and insulin in a cohort of weight-reduced obese Women who have attained and maintained a normal BMI For more than 1 year with the levels in cohorts of never- Obese and currently obese women. Weight-reduced Obese women showed decreased plasma concentrations Of leptin and insulin compared with obese women, but These levels remained significantly higher than those of Never-obese women.