Pharmacognostical, Phytochemical Screening, Formulation and Evaluation of Nanophytosomes of Aqueous Extracts of Trigonella foenum graecum., (Fabaceae)”

摘要

Traditional approach is the one of the emerging field of biomedical sciences. In this research work, we have evaluated the traditional approaches of the ancient healer plant T. foenum graecum belonging to fabaceae family. The leaves of T. Foenum graecum was subjected to extraction process, phytochemical analysis, preparation of phytosome and evaluation of its characterization. The scientific data shows that, leave extracts contain flavonoids, alkaloids and glycosides etc., Nanophytosome was prepared by thin layer lipid hydration method. The preparation was evaluated for DSC, FTIR, SEM, TEM and particle size analysis. Recently, Nanophytosome methodology has been fruitfully applied over several well-known natural drugs such as ginseng, green tea hawthorn, olive oil and grape seed etc. Indeed, phytosome are superior to conventional drug delivery systems in terms of the pharmacodynamic and pharmacokinetic properties. This research, we discusses the various aspects, components, methods of preparation of phytosome and their marketed formulations, therapeutic applications along with the recent research work reported on this technology.