Dexmedetomidine-ketamine versus propofol-ketamine for sedation during upper gastrointestinal endoscopy in hepatic patients (a comparative randomized study)

摘要

Background Cirrhotic patients are more vulnerable to sedation-related complications than the general population, and there is no consensus on sedation during endoscopic procedures for these patients, whose numbers are increasing globally. Our study compared the efficacy of sedation, hemodynamic, respiratory effects, the incidence of side effects, and patient and endoscopist satisfaction with dexmedetomidine-ketamine versus propofol-ketamine during upper gastrointestinal endoscopy (UGIE) in hepatic patients with Child-Pugh classification AandB.