Neuroepithelial Transforming Protein 1 Short Interfering RNA–Mediated Gene Silencing With Microbubble and Ultrasound Exposure Inhibits the Proliferation of Hepatic Carcinoma Cells In Vitro

摘要

Short interfering RNA (siRNA) has been used to knock down the expression of targeted genes in a process known as RNA interference. However, the key to RNA interference is the efficient intracellular delivery of the siRNA. In this study, we sought to enhance the efficiency of transduction and find a novel therapy for hepatic carcinoma.