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Neuroimaging characterization of recovery of impaired consciousness in patients with disorders of consciousness

机译:患有意识障碍患者患者患者受损意识恢复的神经影像学

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Elucidation of critical brain areas or structures that are responsible for recovery of impaired consciousness in patients with disorders of consciousness is important because it can provide information that is useful when developing therapeutic strategies for neurorehabilitation or neurointervention in patients with disorders of consciousness. In this review, studies that have demonstrated brain changes during recovery of impaired consciousness were reviewed. These studies used positron emission tomography, electroencephalography/transcranial magnetic stimulation, diffusion tensor tractography, and diffusion tensor tractography/electroencephalography. The majority of these studies reported on the importance of supratentorial areas or structures in the recovery of impaired consciousness. The important brain areas or structures that were identified were the prefrontal cortex, basal forebrain, anterior cingulate cortex, and parietal cortex. These results have a clinically important implication that these brain areas or structures can be target areas for neurorehabilitation or neurointervention in patients with disorders of consciousness. However, most of studies were case reports; therefore, further original studies involving larger numbers of patients with disorders of consciousness are warranted. In addition, more detailed information on the brain areas or structures that are relevant to the recovery of impaired consciousness is needed.
机译:阐明负责患有意识障碍患者患者患者的患者恢复的关键脑区或结构是重要的,因为它可以提供在发育意识障碍患者患者的治疗策略时可用的信息。在本综述中,综述了在恢复损害意识恢复过程中表现出大脑变化的研究。这些研究使用了正电子发射断层扫描,脑电图/经颅磁刺激,扩散张测牵引和扩散张量牵引/脑电图。这些研究中的大多数研究报告了超前地区或结构在遭受意识受损的重要性。鉴定的重要大脑区域或结构是前额外的皮质,基础前脑,前刺刺,皮质和榫氏皮质。这些结果具有临床上的重要意义,即这些脑区域或结构可以是神经孢子症或神经治疗患者患者的目标区域。但是,大多数研究都有报告;因此,有必要提供涉及更多患有意识障碍患者的进一步原创研究。此外,需要有关与恢复意识恢复相关的大脑区域或结构的详细信息。

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