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OmniMapFree: A unified tool to visualise and explore sequenced genomes

机译:Omnimapfree:一个统一的工具,可视化和探索测序基因组

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? Background Acquiring and exploring whole genome sequence information for a species under investigation is now a routine experimental approach. On most genome browsers, typically, only the DNA sequence, EST support, motif search results, and GO annotations are displayed. However, for many species, a growing volume of additional experimental information is available but this is rarely searchable within the landscape of the entire genome. ? Results We have developed a generic software which permits users to view a single genome in entirety either within its chromosome or supercontig context within a single window. This software permits the genome to be displayed at any scales and with any features. Different data types and data sets are displayed onto the genome, which have been acquired from other types of studies including classical genetics, forward and reverse genetics, transcriptomics, proteomics and improved annotation from alternative sources. In each display, different types of information can be overlapped, then retrieved in the desired combinations and scales and used in follow up analyses. The displays generated are of publication quality. ? Conclusions OmniMapFree provides a unified, versatile and easy-to-use software tool for studying a single genome in association with all the other datasets and data types available for the organism.
机译:?背景技术在调查中获取和探索整个基因组序列信息现在是一种常规的实验方法。在大多数基因组浏览器上,通常只显示DNA序列,EST支持,图案搜索结果和GO注释。然而,对于许多物种,可以获得越来越大的额外实验信息,但在整个基因组的景观中很少可搜索这一点。 ?结果我们开发了一种通用软件,允许用户全部查看单个基因组,也可以在单个窗口中的染色体或超级Contig上下文中查看单个基因组。该软件允许基因组以任何尺度显示和任何功能。将不同的数据类型和数据集显示到基因组上,这些研究已经从其他类型的研究中获取,包括古典遗传学,前瞻性和逆向遗传,转录组科,蛋白质组学学和从替代来源的改进的注释。在每个显示中,可以重叠不同类型的信息,然后以所需的组合和缩放检索并在后续分析中使用。生成的显示器具有发布质量。 ?结论OmnimapFree提供了一个统一,多功能和易于使用的软件工具,用于研究单个基因组,与所有其他数据集和可用于生物体的数据类型。

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