Fabrication of Miniaturized Paper-Based Microfluidic Devices (MicroPADs)

摘要

for 48?hours, devices were miniaturized by 78% in surface area, and this treatment allowed for the fabrication of functional channels with widths as small as 301?μm and hydrophobic barriers with widths as small as 387?μm. The miniaturized devices were shown to be compatible with redox-based colorimetric assays and enzymatic reactions. This miniaturization technique provides a new option for fabricating sub-millimeter-sized features in paper-based fluidic devices without requiring specialized equipment and could enable new capabilities and applications for microPADs.