Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia

Isabelle Durand-Joly; Serge Alfandari; Zinnédine Benchikh; Marion Rodrigue; Ana Espinel-Ingroff; Benoit Catteau; Christophe Cordevant; Daniel Camus; Eduardo Dei-Cas; Francis Bauters; Laurence Delhaes; Stéphane De Botton

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Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia

机译：伏立康唑和两性霉素B-脂质复合物治疗急性白血病患者的皮肤局部传播性镰刀菌感染的成功结果

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摘要

A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.

机译：在诱导化疗期间，一名患有B急性白血病复发的女性中，诊断出具有皮肤定位的弥散性 Fusarium oxysporum 感染，并伴有皮肤定位。感染仅对两性霉素B-脂质复合物难治，但加入伏立康唑后可成功应对。 展开▼

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《Journal of Clinical Microbiology》 |2003年第10期|共3页

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Isabelle Durand-Joly; Serge Alfandari; Zinnédine Benchikh; Marion Rodrigue; Ana Espinel-Ingroff; Benoit Catteau; Christophe Cordevant; Daniel Camus; Eduardo Dei-Cas; Francis Bauters; Laurence Delhaes; Stéphane De Botton;
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中图分类医学微生物学（病原细菌学、病原微生物学）;

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专利

1. Successful treatment with voriconazole for disseminated cutaneous and visceral infection by Fusarium solani in a patient with acute myeloid leukemia [J] . Muramatsu T, Ueki T, Ohashi K, 臨床血液 . 2006,第8期

机译：伏立康唑成功治疗溶胶性镰刀菌引起的皮肤和内脏弥漫性感染

2. Successful treatment with voriconazole for disseminated cutaneous and visceral infection by Fusarium solani in a patient with acute myeloid leukemia [J] . Muramatsu T, Ueki T, Ohashi K, 臨床血液 . 2006,第8期

机译：用急性髓性白血病的患者诱发镰刀菌镰刀唑莫里昂的皮肤和内脏感染成功治疗

3. Treatment of a Locally Invasive Cutaneous Fusarium Species Infection With Voriconazole and Liposomal Amphotericin B in a Patient With Relapsed Acute Myeloid Leukemia [J] . SARA ANNE MEYER, BRUCE M. JONES Journal of the advanced practitioner in oncology . 2017,第5期

机译：用复合急性髓性白血病患者患有伏立康唑和脂质体两性霉素B的局部侵入皮肤镰刀菌物种感染

4. Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study [D] . Harada Yasuhiko, 原田靖彦 2019

机译：根据2017年日本成人白血病研究组（JALSG）AML201研究治疗的成人急性髓性白血病患者的遗传学预测，根据2017 ELN风险分层进行预后分析

5. Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia [O] . Isabelle Durand-Joly, Serge Alfandari, Zinnédine Benchikh, 2003

机译：伏立康唑和两性霉素B-脂质复合物治疗急性白血病的皮肤局部成功传播镰刀菌感染的结果

6. Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia [O] . Durand-Joly, Isabelle, Alfandari, Serge, Benchikh, Zinnédine, 2003

机译：伏立康唑和两性霉素B-脂质复合物治疗急性白血病的成功的局部皮肤弥漫性镰刀菌感染的结果。

1. 糖尿病患者的致命性真菌感染：两性霉素B脂质复合物的治疗 [J] . Bade.LM . 世界医学杂志 . 1998,第011期

2. 两性霉素B雾化吸入加局部灌注联合伏立康唑治疗侵袭性肺部真菌感染研究 [J] . 郭海健 ,彭春玲 ,刘小霞 . 实用临床医药杂志 . 2020,第014期

3. 白血病合并侵袭性真菌感染的疗效及不良反应探讨国产伏立康唑与两性霉素B治疗急性 [J] . 汪虎 . 保健文汇 . 2019,第005期

4. 两性霉素B和伏立康唑治疗儿童急性淋巴细胞性白血病化疗期侵袭性真菌感染分析 [J] . 易雪岚 ,冒青 ,蒋焰 . 中国实验血液学杂志 . 2017,第006期

5. 国产伏立康唑与两性霉素B治疗急性白血病合并侵袭性真菌感染的临床分析 [J] . 王萍 ,张佳佳 ,刘晓娟 . 北方药学 . 2017,第001期

6. 特比萘芬治疗非皮肤癣菌与皮肤癣菌混合感染所致的趾甲真菌病的疗效与安全性 [C] . 陈红清 . 中华医学会第十次全国皮肤性病学术会议 . 2002

7. 串珠镰刀菌致小鼠局部皮肤感染实验研究 [A] . 王胜 . 2011

1. 注射用两性霉素B脂质复合物及其制备方法 [P] . 中国专利： CN101797264B . 2012.05.30

2. 注射用两性霉素B脂质复合物及其制备方法 [P] . 中国专利： CN101797264A . 2010-08-11

3. METHOD FOR PREDICTING SURGICAL INTERVENTION OUTCOME WHEN TREATING PRIMARY INTRACEREBRAL HEMORRHAGES OF SUPRATENTORIAL LOCALIZATION IN AGED PATIENTS IN ACUTE PERIOD [P] . 外国专利： RU2218860C2 . 2003-12-20

机译：在急性期治疗老年患者幕上性局灶性原发性脑室内出血时预测手术干预结果的方法

4. antimicrobial composition, methods of preventing and / or treating an affliction, a patient for a common cold and / or respiratory distress caused by a microbial infection, an infection in a patient's mammalian tissue, decolonizing at least a portion of the nasal cavities, anterior nostrils and / or nasopharynx, at least a portion of the throat / esophagus and at least a portion of the oral cavity of a microorganism patient, killing or inactivating microorganism, providing residual antomicrobial efficacy on a surface and a bored mammal of a patient, treat a middle ear infection, chronic sinusitis and impetigo on the skin and a burn, manufacture an antimicrobial composition, and release an antimicrobial component to a surface, and release system for an antimicrobial component. [P] . 外国专利： BRPI0414220A . 2006-10-31

机译：抗菌组合物，预防和/或治疗疾病的方法，患者因微生物感染引起的普通感冒和/或呼吸窘迫，患者哺乳动物组织的感染，使至少一部分鼻腔非殖民化，前鼻孔和/或鼻咽，至少一部分微生物患者的喉咙/食道和至少一部分口腔，杀死或灭活微生物，在患者的表面和无聊的哺乳动物上提供残留的抗微生物功效，治疗中耳感染，皮肤上的慢性鼻窦炎和脓疱疮和烧伤，制造抗菌组合物，并将抗菌成分释放到表面，以及释放抗菌成分的系统。

5. METHOD FOR DETERMINING THE CRITERIA gemostaziologicheskie adverse outcomes sepsis in patients with acute myeloid leukemia [P] . 外国专利： RU2006124165A . 2008-01-20

机译：急性髓细胞性白血病患者的判断标准

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Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia

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