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Dynamics of Language Reorganization after Stroke in Patients with Left Frontal Lesions

机译:左额叶病变患者中风后语言重组的动态

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In a longitudinal fMRI study on aphasic patients (Saur et al., 2006) an overall pattern of languagereorganization, proceeding in three phases, was described with (i) reduced activation of left languageareas in the acute, (ii) an upregulation of the entire language network with recruitment ofhomologous language regions (with highest activation in right frontal areas) in the subacute and (iii)a normalization of activation in the chronic phase. However, this pattern was derived from aheterogeneous group of aphasic patients with different lesion sites. The aim of this study was todescribe reorganization processes in a group of aphasic patients with exclusively left frontal lesions.
机译:在一项针对失语症患者的纵向fMRI研究中(Saur等人,2006年),语言重组的总体模式分三个阶段进行了描述:(i)急性期左语言区域的激活减少;(ii)整个语言结构的上调语言网络,在亚急性中招募同源语言区域(在右额叶区域具有最高的激活),并且(iii)在慢性期激活正常化。然而,这种模式源自具有不同病变部位的非均质性失语患者组。这项研究的目的是描述一群完全患有左额叶病变的失语症患者的重组过程。

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