Resent studies suggest that spelling mechanisms are subserved by specific areas of the lefthemisphere, and atrophy in these areas is correlated with breakdown of spelling mechanisms(Sepelyak et al., 2011). There is evidence that inferior frontal gyrus (IFG) and the supramarginalgyrus (SMG) are areas that subserve phoneme-grapheme conversion (PGC), and IFG and fusiformgyrus (FG) subserve lexical access mechanisms. Our aim was to determine whether transcranialdirect current stimulation (tDCS) applied at related spelling areas would improve spellingperformance in individuals with primary progressive aphasia (PPA), a neurodegenerative diseaseaffecting foremost language abilities. Spelling is affected early in PPA, especially in semantic andlogopenic variants. Dysgraphia can be very disabling in today’s society.
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