Paradoxical effect of lenalidomide on cytokine|[sol]|growth factor profiles in multiple myeloma

摘要

Background:Lenalidomide is an active immunomodulatory and antiproliferative agent in multiple myeloma. However, the molecular mechanisms driving these activities are not yet fully elucidated. Therefore, we investigated the modulation of the cytokine/growth factor patterns of myeloma cells under LEN treatment.