首页> 外文期刊>British Journal of Cancer >PI3K|[sol]|Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma
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PI3K|[sol]|Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma

机译:PI3K | [sol] | Akt信号传导对于转移性肝硬化胃癌的附着,扩散和体内生长是必需的

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摘要

Background:PI3K/Akt (PKB) pathway has been shown in several cell types to be activated by ligands to cell surface integrins, leading to the metastasis of tumour cells. The signalling pathways involved in the metastatic spread of human scirrhous gastric carcinoma cells have not been defined.
机译:背景:PI3K / Akt(PKB)途径已在多种细胞类型中被配体激活,并被细胞表面整联蛋白激活,从而导致肿瘤细胞转移。尚未定义人肝硬化胃癌细胞转移扩散的信号通路。

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