Fermenters in Human Infections with Special Reference to Acinetobacter Species in A Tertiary Care Hospital from North Karnataka.

摘要

Background: Non-fermenters are a group ofaerobic non-spore forming gram negativebacilli that are either incapable of utilizingcarbohydrates as a source of energy or degradethem via oxidative rather than fermentativepathway. These are increasingly been reportedfrom the cases of nosocomial infections. Aimsand Objectives: This study was undertakenaiming to identify, characterize all non-fermenters and further study of Acinetobacterisolates. Materials and Methods: A total 116non-fermenters isolated from variousspecimens obtained from the patients in tertiarycare hospital. Gram negative bacilli whichfailed to produce acid on Triple Sugar Iron Agar(TSI) were identified by employing battery oftests. The Acinetobacter isolates were furtherspeciated and antimicrobial susceptibilitytesting done by Kirby Bauer disc diffusiontechnique. Results: Non-fermenters isolatedwere Pseudomonas aerugionsa (69.8%),Acinetobacter species (18.9%),Stenotrophomonas maltophilia (4.3%),Burkholderia cepacia (3.4%), Alcaligenesfecalis (1.7%) and Pseudomonas fluorescens(1.7%). Most of the isolates showedsusceptibility to imipenem (86.3%) whereasnone of the isolates were sensitive tocephalexin and co-trimoxazole. Conclusion:This study highlights that, after Pseudomonasaeruginosa, Acinetobacter species is the mostcommon non-fermenter. Majority of theisolates of Acinetobacter Species were ofnosocomial origin and were multidrugresistant, which underlines the importance ofproper vigilance of these infections inhospital setting.