...
首页> 外文期刊>Journal of International Medical Research >Complete resolution of avascular necrosis of the human femoral head treated with adipose tissue-derived stem cells and platelet-rich plasma
【24h】

Complete resolution of avascular necrosis of the human femoral head treated with adipose tissue-derived stem cells and platelet-rich plasma

机译:脂肪组织衍生的干细胞和富含血小板的血浆治疗可完全解决股骨头缺血性坏死

获取原文
   

获取外文期刊封面封底 >>

       

摘要

We report a case of a 43-year-old man with early stage (stage 1) avascular necrosis (AVN) of the femoral head treated with adipose tissue-derived stem cells (ASCs) and platelet-rich plasma (PRP). ASC-containing stromal vascular fraction was mixed with PRP and hyaluronic acid. This mixture was then injected into the diseased hip under ultrasound guidance. The affected hip was reinjected weekly with additional PRP for 4 weeks. The patient was followed-up with sequential magnetic resonance imaging (MRI) scans at 3, 18, and 21 months after treatment, together with Visual Analogue Scale (VAS) Walking Index, Functional Rating Index, Harris Hip Score, and Range of Motion (ROM) assessments. The patient’s severe hip pain was considerably improved at 3 months after treatment, with pain scores, ROM and MRI showing near complete resolution of AVN. Pain scores, ROM and MRI at 18 and 21 months after treatment indicated complete resolution of AVN. This case represents the first evidence of complete resolution of early stage AVN of the hip following treatment with ASCs/PRP.
机译:我们报道了一名43岁男性,患有脂肪组织衍生干细胞(ASC)和富含血小板的血浆(PRP)治疗的股骨头早期(1期)血管坏死(AVN)。将含有ASC的基质血管部分与PRP和透明质酸混合。然后在超声引导下将该混合物注射到患病的臀部。每周重新注入患病的髋关节,并附加PRP,持续4周。对该患者在治疗后3、18和21个月进行了连续磁共振成像(MRI)扫描,以及视觉模拟量表(VAS)步行指数,功能评分指数,Harris髋关节得分和运动范围( ROM)评估。治疗后3个月,患者的严重髋部疼痛得到了明显改善,疼痛评分,ROM和MRI显示AVN几乎完全消失。治疗后18和21个月的疼痛评分,ROM和MRI显示AVN完全消失。该病例代表了用ASCs / PRP治疗后髋关节早期AVN完全消退的第一个证据。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号