Clinical observation of Jiangzhi Hugan Recipe combined with rosuvastatin calcium tablets in the treatment of non-alcoholic fatty liver disease

摘要

Objective: To investigate the influence of integrated traditional Chinese and Western medicineon the related indexes and TCM syndrome scores of patients with non-alcoholic fatty liverdisease. Methods: A total of 128 patients with non-alcoholic fatty liver disease who wereadmitted to our department from January 2017 to May 18, 2017 were enrolled in the study.According to the hospital admission record number, they were randomly divided intotreatment groups (64 cases). and the control group (64 cases). The control group was treatedwith rosuvastatin calcium tablets. The treatment group was treated with Jiangzhi FangganRecipe on the basis of the control group. The treatment was performed for 10 d for a total of3 courses. Comparison of liver function, blood lipids, insulin resistance index (HOMA-IR),iris (Irisin), superoxide dismutase (SOD), malondialdehyde (MDA), body mass index (BMI),waist circumference (WC), Liver/spleen CT ratio and TCM syndrome scores. Results: Thecurative effect of TCM symptom in the treatment group (82.82%) was significantly higherthan that in the control group (65.62%), and the difference was statistically significant. Therewas no difference between the two groups before treatment. Compared with before treatment,the levels of each index were significantly improved after treatment, and the improvementof the treatment group was more significant than that of the control group. Conclusion: Thecombination of traditional Chinese and Western medicine can improve the symptoms ofpatients, achieve good clinical efficacy, and have certain anti-oxidative stress effects, which isworthy of clinical promotion or further research.