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There is no age limit for methadone: a retrospective cohort study

机译:美沙酮没有年龄限制:一项回顾性队列研究

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Background Data from the US indicates that methadone-maintained populations are aging, with an increase of patients aged 50 or older. Data from European methadone populations is sparse. This retrospective cohort study sought to evaluate the age trends and related developments in the methadone population of Basel-City, Switzerland. Methods The study included methadone patients between April 1, 1995 and March 31, 2003. Anonymized data was taken from the methadone register of Basel-City. For analysis of age distributions, patient samples were split into four age categories from '20-29 years' to '50 years and over'. Cross-sectional comparisons were performed using patient samples of 1996 and 2003. Results Analysis showed a significant increase in older patients between 1996 and 2003 (p < 0.001). During that period, the percentage of patients aged 50 and over rose almost tenfold, while the proportion of patients aged under 30 dropped significantly from 52.8% to 12.3%. The average methadone dose (p < 0.001) and the 1-year retention rate (p < 0.001) also increased significantly. Conclusions Findings point to clear trends in aging of methadone patients in Basel-City which are comparable, although less pronounced, to developments among US methadone populations. Many unanswered questions on medical, psychosocial and health economic consequences remain as the needs of older patients have not yet been evaluated extensively. However, older methadone patients, just as any other patients, should be accorded treatment appropriate to their medical condition and needs. Particular attention should be paid to adequate solutions for persons in need of care.
机译:美国的背景数据表明,美沙酮维持的人群正在老龄化,年龄在50岁或50岁以上的患者有所增加。欧洲美沙酮人群的数据很少。这项回顾性队列研究旨在评估瑞士巴塞尔市美沙酮人群的年龄趋势和相关发展。方法该研究纳入了1995年4月1日至2003年3月31日期间的美沙酮患者。匿名数据来自巴塞尔市美沙酮登记册。为了分析年龄分布,将患者样本分为从“ 20-29岁”到“ 50岁及以上”的四个年龄类别。使用1996年和2003年的患者样本进行横断面比较。结果分析显示,在1996年至2003年之间,老年患者显着增加(p <0.001)。在此期间,年龄在50岁及以上的患者比例上升了近十倍,而年龄在30岁以下的患者比例从52.8%大幅下降至12.3%。美沙酮的平均剂量(p <0.001)和1年保留率(p <0.001)也显着增加。结论结论表明,巴塞尔市美沙酮患者的年龄增长趋势清晰,尽管趋势不明显,但与美国美沙酮人群的发展趋势相当。由于尚未对老年患者的需求进行广泛评估,因此有关医学,心理和健康经济后果的许多悬而未决的问题仍然存在。但是,与其他患者一样,老年美沙酮患者也应根据其医疗状况和需要接受适当的治疗。应特别注意为需要护理的人提供适当的解决方案。

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