Enfermedad de Parkinson y factores ambientales. Un estudio caso-control

摘要

The Parkinson Disease (PD) has been related to different environmental factors that increise their prevalence. Objective: To assess the relation between the PD and the environmental factors, in persons registered in the Primary Health Care System in Concepción, Chile. Methodology: A case-control study was conducted matched by age and gender, in a sample of 126 people, distributed in 63 cases and 63 controls. Gross and adjusted Odds Ratio (OR) were estimated through multivariate logistic regression models. Results: The mean age was 71 for the cases and 72 for the controls. The history of toxic exposure is 3 times more frequent in the women of the case group than in the control group (75%; CI95% 17,6-97,6 vs 25%; CI95% 23,2-82,3). The risk of PE increases in people who have been exposed to toxicants (OR: 2.9; CI95% 1.2-7.1). Conclusion: This article confirms association between exposure to toxicants and PD.