Radiation transport calculations for the new ion beam laboratory at Sandia National Laboratory

摘要

The 252 Cf brachytherapy reduces the effect caused by the tumor hypoxia in photon radiotherapy and chemotherapy. The AAPM TG-43 modified formalism was used for the calculation of the fast neutron absorbed dose rate of 252 Cf brachytherapy sources for normal tissues and malignant tumors. Three models of HDR 252 Cf sources; AT, VariSource and μSelectron were simulated using spherical geometry, Watt fission spectrum and the MCNPX code. The results show that small variations in the elemental composition between the normal tissues and malignant tumors, produce variations in the reference fast neutron absorbed dose rate up to 14%.