Successful mobilization of the resources of universities can have a positive effect on regional economies; even more so in peripheral regions. The role of universities in regional development, innovation and growth comes into even sharper focus with the emergence of ‘smart specialization’ strategies, an ex-ante conditionality for accessing European Structural Funds from 2014. However, partnerships between universities and regions can fail to achieve their early ambitions, often due to a lack of understanding of each side’s drivers and barriers for cooperation. The collaboration between Region V?rmland and Karlstad University in Sweden demonstrates a systemic and broad-based view of innovation that fits well within the policy framework of European and national innovation strategies. While recognizing the complexities and tensions inherent in such collaborations, this case study provides valuable insights for other European universities, regions and policy-makers in peripheral places that are seeking to work more closely to support smart specialization.
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