Abstract：Objective To investigate the effect of comprehensive nursing intervention on response attitude to disease and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 112 COPD patients were randomly divided into the observation group and the control group, with 56 cases in each group. Both two groups were given routine nursing care and the observation group was applied with extra comprehensive nursing intervention. The response attitude to disease was assessed by Mishel uncertainty in illness scale (MUIS) and Herth hope index (HHI). The mental status of patients was assessed by selfrating anxiety scale (SAS). The quality of life was assessed by 36item shortform health survey questionnaire (SF36). Results The observation group had a lower MUIS and a higher HHI compared with the control group after intervention (P＜0.01). The proportion of patient with severe anxiety according to the SAS was significant lower in observation group than that of controls (P＜0.05). Scores of role emotion, mental health, physiology function and social relation in SF36 were higher in the observation group than those in the control group (P＜0.01).Conclusion Comprehensive nursing intervention can improve the response attitude to disease and quality of life in COPD patients.
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