Study of Topical Placental Extract versus Povidone Iodine and Saline Dressing in Various Diabetic Wounds

摘要

AIM : To compare topical placental extract versus povidone iodine and saline dressing in various diabetic wounds. METHOD : 60 cases of diabetic wound included which was admitted in SMIMER during September 2010 to august 2012. After complete debridement of wound 30 cases were applied povidone iodine and normal saline, and rest 30 case were applied placental extract till second surgery or wound treated. And outcome compared in form of healing rate, infection clearance, time of second surgery, hospital stay and duration of treatment. RESULT : In study average duration on complete granulation tissue in placental extract dressing is 15.2 day in comparison to povidone iodine which had 24.46 day. In placental group 12 cases treated conservative and 18 needed surgical intervention in compare to povidone group having result 10 and 7. Total duration of treatment and hospital stay is less in placental group in compare to povidone group. CONCLUSION : Diabetics are predispose to development of foot lesions. It increases rate of infection mainly due to higher glucose concentration. Longer the duration of diabetes are more prone for surgical complication. In study, the use of placental extract increases a rate of wound healing due to presence of amino acids, vitamins, nucleotides in it. And patients having early recovery average 7-10 days.