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首页> 外文期刊>MBio >Correction for Herrera et al., The Vibrio cholerae VprA-VprB Two-Component System Controls Virulence through Endotoxin Modification
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Correction for Herrera et al., The Vibrio cholerae VprA-VprB Two-Component System Controls Virulence through Endotoxin Modification

机译:对Herrera等人的修正,霍乱弧菌 VprA-VprB两组分系统通过内毒素修饰控制毒力

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AUTHOR CORRECTION Volume 5, no. 6, doi: 10.1128/mBio.02283-14 , 2014. In Results, in the paragraph headed “The VprA-VprB two-component system responds to polymyxin, bile, and mildly acidic pH” (PDF page?5), the fourth and fifth sentences should be modified to read as follows (revised text is indicated in bold): “Alternatively, when wild-type cells were exposed to divalent cations such as Ca~(2+)(10?mM) and Mg~(2+)(10?mM), vprA and almE synthesis was downregulated. It has been reported that a small, but statistically significant, change in the expression of vc1319-vc1320 , also known as carS-R , occurs during growth of V.?cholerae in the presence of Ca~(2+)(77). However, in the current work, statistically significant changes were observed only in almE transcripts (see Fig.?S5A in the supplemental material), suggesting that V.?cholerae moderately responds to divalent cations with a predicted reduction in glycine-lipid A modification.” In Discussion (PDF page?8), the end of paragraph?5 should read as follows (revised text is indicated in bold): “Overall, this study establishes that the VprAB TCS positively regulates the almEFG operon to control glycine-lipid A modification (Fig.?7). Furthermore, the current work is consistent with previous microarray data which show that vc1319-vc1320 is involved in alm gene expression (77).” In References, due to the new text indicated above, the following reference should be added. 77. Bilecen K, Yildiz FH. 2009. Identification of a calcium-controlled negative regulatory system affecting Vibrio cholerae biofilm formation. Environ Microbiol 11:2015–2029. doi:10.1111/j.1462-2920.2009.01923.x.
机译:作者更正第5卷,第。 6,doi:10.1128 / mBio.02283-14,2014。在结果中,标题为“ VprA-VprB两组分系统对多粘菌素,胆汁和弱酸性pH有反应”(PDF第5页)。第五句应修改为以下内容(修改后的文字以粗体显示):“或者,当野生型细胞暴露于Ca〜(2 +)(10?mM)和Mg〜(2 +)(10?mM),vprA和almE合成被下调。据报道,在有Ca〜(2 +)(77)存在的霍乱弧菌生长期间,vc1319-vc1320(也称为carS-R)的表达发生了微小但有统计学意义的变化。但是,在当前的工作中,仅在almE转录本中观察到统计学上的显着变化(参见补充材料中的图S5A),这表明霍乱弧菌对二价阳离子有中等反应,并预测甘氨酸-脂质A修饰的减少。 ”在“讨论”(PDF第8页)中,第5段的末尾应如下所示(修改后的文本以粗体显示):“总体而言,该研究确定VprAB TCS积极调节almEFG操纵子以控制甘氨酸-脂质A修饰(图7)。此外,当前的工作与以前的微阵列数据一致,后者显示vc1319-vc1320参与alm基因表达(77)。”在参考文献中,由于上述新文本,应添加以下参考文献。 77. Bilecen K,Yildiz FH。 2009。确定影响霍乱弧菌生物膜形成的钙控制的负调控系统。环境微生物学11:2015-2029。 doi:10.1111 / j.1462-2920.2009.01923.x。

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